Myeloperoxidase Genotype, Fruit and Vegetable Consumption, and Breast Cancer Risk
نویسندگان
چکیده
منابع مشابه
Myeloperoxidase genotype, fruit and vegetable consumption, and breast cancer risk.
Myeloperoxidase (MPO), an antimicrobial enzyme in the breast, generates reactive oxygen species (ROS) endogenously. An MPO G463A polymorphism exists in the promoter region, with the variant A allele conferring lower transcription activity than the common G allele. Because oxidative stress may play a role in breast carcinogenesis, we evaluated MPO genotypes in relation to breast cancer risk amon...
متن کاملAssociations between breast cancer risk and the catalase genotype, fruit and vegetable consumption, and supplement use.
Observed weak or null associations between fruit and vegetable intake and breast cancer risk could be due to heterogeneity in endogenous antioxidant capabilities. The authors evaluated potential relations between a functional polymorphism in catalase, an antioxidant enzyme, and breast cancer risk, particularly in relation to fruit and vegetable intake and supplement use. Women (1,008 cases and ...
متن کاملOxidative stress-related genotypes, fruit and vegetable consumption and breast cancer risk.
Dietary antioxidants may interact with endogenous sources of pro- and antioxidants to impact breast cancer risk. A nested case-control study of postmenopausal women (505 cases and 502 controls) from the Cancer Prevention Study-II Nutrition Cohort was conducted to examine the interaction between oxidative stress-related genes and level of vegetable and fruit intake on breast cancer risk. Genetic...
متن کاملFruit and vegetable consumption.
OBJECTIVES This article focuses on associations between the frequency of fruit and vegetable consumption and other health-related behaviours or conditions, including physical activity, smoking, obesity and alcohol-dependence. DATA SOURCE The data are from the first half of cycle 1.1 of the Canadian Community Health Survey, collected from September 2000 through February 2001. ANALYTICAL TECH...
متن کاملLow fruit and vegetable consumption
This analysis assessed the levels of mean dietary intakes of fruit and vegetables (excluding potatoes) measured in grams per day. The theoreticalminimum-risk distribution for fruit and vegetable intake was estimated to be 600g/day in adults, 480g/day in children aged 5–14 years, and 330g/day in children aged 0–4 years. It is proposed to use set intervals of 80g/day of fruit and vegetables (equi...
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ژورنال
عنوان ژورنال: Cancer Research
سال: 2004
ISSN: 0008-5472,1538-7445
DOI: 10.1158/0008-5472.can-04-1843